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Artigos Médicos

Dedicamos este espaço aos médicos que desejam manter-se constantemente atualizados no campo da Medicina Reprodutiva. Aqui, vocês encontrarão os artigos mais relevantes, não exclusivamente de autoria da Equipe VILARA, publicados em revistas especializadas. A Equipe VILARA tem se destacado no cenário nacional e internacional pelos trabalhos científicos publicados em diversos congressos da especialidade.

Endometrial gene expression in the window of implantation is altered in obese women especially in association with polycystic ovary syndrome.

Authors: J Bellver, J A Martınez-Conejero, E Labarta, P Alama, Marco Melo, J Remohı, A Pellicer, J A Horcajadas (Fertility & Sterility 95: 2335–2341, 2011) OBJECTIVE: To determine whether luteal phase endometrial transcriptome is altered in obese women during the window of implantation (WOI), considering the presence of infertility, fat distribution and association with polycystic […]

Expression of p53, Ki-67, and CD31 Proteins in Endometrial Polyps of Postmenopausal Women Treated With Tamoxifen.

Authors: Miranda SP, Traiman P, Cândido EB, Lages EL, Freitas GF, Lamaita RM, Vidigal PV, da Silva Filho AL. (Int J Gynecol Cancer- 2010; 20(9):1525-30) Abstract This study was undertaken to investigate the expression of p53, Ki-67, and CD31 proteins in endometrial polyps of postmenopausal women treated with tamoxifen (TAM). Postmenopausal women with endometrial polyps […]

A prospective, randomized, controlled trial comparing three different gonadotropin regimens in oocyte donors: ovarian response, in vitro fertilization outcome, and analysis of cost minimization

Authors: Marco Melo, Jose Bellver, Nicolas Garrido, Marcos Meseguer, Antonio Pellicer, Jose Remohı (Fertility & Sterility 94: 958- 964, 2010) Objective: To compare the efficacy of three different gonadotropin regimens in an oocyte donation program. The analysis of cost minimization also was evaluated. Design: Prospective, randomized, controlled study. Setting: Instituto Universitario–IVI, Valencia, Spain. Patient(s): One […]

GnRH agonist administration at the time of implantation does not improve pregnancy outcome in intrauterine insemination cycles: a randomized controlled trial

Authors: Jose Bellver, Elena Labarta, Ernesto Bosch, Marco Melo, Carmina Vidal, Jose Remoh, and Antonio Pellicer (Fertility & Sterility 94: 1065- 1071, 2010) Objective: To assess whether GnRH agonist administration in the luteal phase improves pregnancy outcome in intrauterine insemination (IUI) cycles. Design: Single-center, randomized, single-blind, placebo-controlled trial. Setting: University-affiliated infertility clinic, between February 2005 […]

Y chromosome microdeletions, sperm DNA fragmentation and sperm oxidative stress as causes of recurrent spontaneous abortion of unknown etiology

Auhtors: J. Bellver, M. Meseguer, L. Muriel, S. Garcıía-Herrero, Marco Melo, A.L. Garda, J. Remohı, A. Pellicer, N. Garrido (Human Reproduction 25: 1713-1721, 2010) Background: The aim of the present study was to evaluate the implication of male factor, in terms of sperm DNA oxidation and fragmentation, and Y chromosome microdeletions in recurrent spontaneous abortion […]

Female obesity impairs in vitro fertilization outcome without affecting embryo quality

Authors: Jose Bellver, Yanira Ayllon, Marcos Ferrando, Marco Melo, Eduardo Goyri, Antonio Pellicer, Jose Remohı, Marcos Meseguer. (Fertility & Sterility 2010; 93:447–454) OBJECTIVE: To compare embryo quality and reproductive outcome in our IVF program according to the women’s body mass index (BMI). DESIGN: Retrospective study. SETTING: University-affiliated infertility clinic, January 2001 and April 2007. PATIENTS: […]

Comparison of IVF outcome in an oocyte donation program using triptorelin or rhCG as trigger oocyte

Authors: Marco Melo, Cristiano E. Busso, José Bellver, Pilar Alama, Nicolas Garriso, Marcos Meseguer, Antonio Pellicer, José Remohí (Reproductive BioMedicine Online 2009; 19(4): 486-492) The use of GnRH agonists for triggering ovulation is still a controversy. Few reports are available on this issue. The primary objective was to evaluate the clinical outcome associated with GnRH […]

AFC can be utilized in the prediction of ovarian response, but can not predict the oocyte/ embryo quality or the IVF outcome in an egg donation program.

Authors: Marco Melo, Nicolás Garrido, Claudio Alvarez, José Bellver, Marcos Meseguer, Antonio Pellicer, José Remohí. (Fertility and Sterility 2009; 91: 148-156) OBJECTIVE: The aim of this study was to verify whether the use of AFC could predict ovarian response, oocyte/embryo quality and IVF outcome. DESIGN: Prospective study SETTING: Instituto Universitario%u2014IVI, Valencia, Spain PATIENTS: 1,074 donors […]

Cigarette smoking and Reproductive function

Authors: Sérgio Reis Soares, Marco Melo (Current Opinion in Obstetrics and Gynecology- 2008; 20: 281-291) Purpose of the review: To perform a systematic review of the literature on the relationship between cigarette smoking and reproductive function. Whenever possible, this review is focused on the most recently published studies (mainly the last two years). However, in […]