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Female obesity impairs in vitro fertilization outcome without affecting embryo quality

Authors: Jose Bellver, Yanira Ayllon, Marcos Ferrando, Marco Melo, Eduardo Goyri, Antonio Pellicer, Jose Remohı, Marcos Meseguer. (Fertility & Sterility 2010; 93:447–454) OBJECTIVE: To compare embryo quality and reproductive outcome in our IVF program according to the women’s body mass index (BMI). DESIGN: Retrospective study. SETTING: University-affiliated infertility clinic, January 2001 and April 2007. PATIENTS: […]

Comparison of IVF outcome in an oocyte donation program using triptorelin or rhCG as trigger oocyte

Authors: Marco Melo, Cristiano E. Busso, José Bellver, Pilar Alama, Nicolas Garriso, Marcos Meseguer, Antonio Pellicer, José Remohí (Reproductive BioMedicine Online 2009; 19(4): 486-492) The use of GnRH agonists for triggering ovulation is still a controversy. Few reports are available on this issue. The primary objective was to evaluate the clinical outcome associated with GnRH […]

AFC can be utilized in the prediction of ovarian response, but can not predict the oocyte/ embryo quality or the IVF outcome in an egg donation program.

Authors: Marco Melo, Nicolás Garrido, Claudio Alvarez, José Bellver, Marcos Meseguer, Antonio Pellicer, José Remohí. (Fertility and Sterility 2009; 91: 148-156) OBJECTIVE: The aim of this study was to verify whether the use of AFC could predict ovarian response, oocyte/embryo quality and IVF outcome. DESIGN: Prospective study SETTING: Instituto Universitario%u2014IVI, Valencia, Spain PATIENTS: 1,074 donors […]

Cigarette smoking and Reproductive function

Authors: Sérgio Reis Soares, Marco Melo (Current Opinion in Obstetrics and Gynecology- 2008; 20: 281-291) Purpose of the review: To perform a systematic review of the literature on the relationship between cigarette smoking and reproductive function. Whenever possible, this review is focused on the most recently published studies (mainly the last two years). However, in […]

Cigarette smoking and IVF

Authors: Sérgio R. Soares, Marco Melo (Expert Review in Obstetrics and Gynecology- 2008; 3(4): 555-563) The goal of this text is to present a thorough review of the literature on the relationship between cigarette smoking and IVF cycles outcome, as well as the possible mechanisms through which tobacco constituents affect these cycles. Whenever possible, this […]

A new safe, simple and successful vitrification method for bovine and human blastocysts

Authors: James Stachecki, John Garrisi, Sandro Sabino, et al. Reproductive Biomedicine Online, Vol: 17, 3, 360-367, 2008 Abstract This study examined a new method for vitrification of blastocysts that is safe, simple and easy to learn and use. Current vitrification techniques have shortcomings that include the use of dimethyl sulphoxide, one of the more toxic […]

HIV infection in serodiscordant couples does not have impact on the embryo quality and ICSI outcome

Authors: Marrco Melo, Marcos Meseguer, José Bellver, José Remohí, Antonio Pellicer, Nicolás Garrido (Fertility and Sterility 2008; 89: 141-150) OBJECTIVE: To evaluate the embryo quality in our program for HIV-1 serodiscordant couples (SDC) with the male infected in comparison with a tubal infertility control group. DESIGN: Retrospective case-control study. SETTING: Instituto Universitario IVI, Valencia, Spain […]

Improvements achieved in an oocyte donation program over 10 years period: sequential increase in implantation and pregnancy rates and decrease in high-order multiple pregnancies.

Authors: Erdal Budak, Nicolas Garrido, Sérgio Reis-Soares, Marco Melo, Marcos Meseguer, Antonio Pellicer, José Remohí (Fertility and Sterility 2007; 88: 342-349) Objective: To compare cycle outcome parameters and cumulative pregnancy rates (CPR) in oocyte donation cycles over a period of 10 years. Design: Retrospective study from a computer database. Oocyte donation cycles with embryo transfer […]

Obesity and poor reproductive outcome: the potential role of the endometrium

Authors: José Bellver, Marco Melo, Ernesto Bosch, Vicente Serra, José Remohí, Antonio Pellicer (Fertility and Sterility 2007; 88: 446-451) OBJECTIVE: We have performed this study to analyze the potential role of extra-ovarian factors, like endometrium, in the reproductive outcome of obese patients. DESIGN: Retrospective study. SETTING: Instituto Universitario IVI, Valencia, Spain. PATIENTS: All first cycles […]

Ovarian stimulation length, number of follicles higher than 17mm and estradiol on the day of hCG.

Authors: Nicolás Garrido, Marco Melo, Carlos Simón, José Remohí, Antonio Pellicer, Marcos Meseguer (Reproductive Medicine and Biology 2007; 6: 19-26) Our aim with this work was to identify the risk factors, their prognostic value on multiple pregnancies (MP) prediction and their thresholds in women undergoing controlled ovarian hyperstimulation (COH) with FSH and intrauterine insemination (IUI). […]